Friday, March 11, 2011

A hope for LCA

A legally sightless, 9-year-old boy since birth had an ailment that would gradually devour hisvision, but has lately been restored to normal eyesight with merely a single shot.

The implausible procedure is a ray of promising hope spelling a conclusion to blindness in some cases. The Geneticists from the University School of Medicine, USA, have successfully snapped the cipher for creating light-receptive seeing cells that would help regain sight in many blind in the UK.

During this path-breaking procedure, Corey Haas was the foremost patient globally to have been given this injection with the innovatory gene therapy following which his vision has become nearly perfect.

Corey was the foremost of the 5 kids and 7 adults with the rare condition LCA or Leber’s congenital amaurosis (affecting 1 in eighty thousand births) were fruitfully cured employing this original procedure.

Eyesight problemsLCA condition severely affects eyesight from birth onwards and gradually leads to total sightlessness.

The utmost progress were noted in kids, most of whom are presently able to plot a course through a low-illuminated obstacle course, that they earlier could not do prior to the treatment.

The jab functions by introducing genes within the body that created light-receptive pigments in the back region of the eye. This helped reinstate those pigments which were earlier damaged due to the condition.

Prior to undergoing the treatment, Corey had lost a major part of his eyesight and was incapable of clearly viewing the board in the classroom and needed huge print electronic screens for helping him view anything.

However, things changed soon following the eye jab and he can easily read the board without the assistance of any electronic medium and even engaging in physical activities with his schoolmates is now possible.

Dr. Katherine High belonging to the Center for Cellular and Molecular Therapeutics at The Children’s Hospital Of Philadelphia has stated that magnificent outcome is a positive change in the total field of gene therapy that would help in reinstating vision among patients that had earlier lost all hopes.

Such revelations could pave way for more R&D work for gene therapy in finding ways of curing the most prevalent retinal problems like age-associated macular degeneration.

Dr. Jean Benett Kirby, an Ophthalmology professor from the University Of Pennsylvania School Of Medicine states that the clinical advantages have been persistent for almost 2 years since the foremost entrants were given retinal jabs of curative genes.

The spectacular outcome has built the base for application of gene therapy to not merely other kinds of infancy-onset retinal conditions, but also for commonly occurring retinal deteriorations.

Dr. Bennett has stated that the newest outcomes are built on about two decades of gene research on heritable sightlessness, commencing with original work conducted on mice and dogs.

Leber’s innate amaurosis is a set of heritable diseases which causes major harm to the light receptors present in the retina thus robbing eyesight.

It generally starts robbing eyesight in early infancy and leads to complete blindness till the person touches ages between 20-30 years. Presently, there is no cure for LCA.

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